Difference Between Phentermine 37.5 and Adipex

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You have probably heard that Adipex and Phentermine 37.5 are two of the most popular and effective prescription weight loss drugs available. However, did you know that Adipex (Adipex-P) is the leading brand name of the generic form of Phentermine Hydrochloride in a 37.5mg dosage? In other words, they are basically the same medication designed to produce the same results with only very minor differences.


The primary differences between Phentermine 37.5 and Adipex are the following:

  • Adipex is the brand name of the diet pill created by GATE Pharmaceuticals. Adipex contains 37.5mg of Phentermine Hydrochloride, which is exactly the same chemical substance and dosage that is used in Phentermine 37.5.
  • Unlike Phentermine 37.5, Adipex contains inactive ingredients, such as colorant and corn starch that have been mixed with the chemical substance to create a product that can be easily ingested and recognized.
  • All generic phentermine diet pills are bioequivalent to brand names, such as Adipex. Bioequivalence means that brand-name medications and their generic equivalents have been carefully studied and compared to ensure that they are the same and do not differ in efficacy, safety and bioavailability when the are taken at the same dosage. Therefore, the active ingredient “phentermine” that exists in both generic tablets and branded diet pills are exactly the same, so when taken as directed you can expect the same results.
  • Aside from actual dosage amounts and pill forms, such is Phentermine 37.5 tablets and Adipex 37.5 capsules, the only real difference that exists between Adipex and Phentermine are the inactive ingredients that have been mixed with the active ingredient. The types of inactive elements that are used can cause diverse effects. For example, the inactive ingredient, resin, slows down the rate at which the body absorbs phentermine.
  • Since everyone’s body processes medication in a different way, some people may react differently to the inactive ingredients in Adipex than others who take the same pill. As a result, certain individuals may find that Adipex is either slightly more effective when compared to other generic phentermine alternatives, such as Phentermine 37.5.
  • Generic medications are often sold at a lower cost than brand names, so Phentermine 37.5 is usually sold at a cheaper price than Adipex.


In essence, Phentermine 37.5 and Adipex are the exact same drug, however Adipex contains some inactive ingredients that may improve its absorption in the body. For this reason, some people find Adipex better than Phentermine, but their effectiveness to suppress appetite, increase metabolism and boost energy levels is relatively the same. Both Phentermine 37.5 and Adipex are prescription weight loss medications and require a doctor's prescription to be legally purchased online or at a pharmacy.


+3 # RE: Wendy 2014-03-31 21:30
I started with phentemine which a hour I took the pill everyday at 5am by 8am I notice I talk too much I had energy and I also sweat a lot and for some reason I was interested in sex I was losing weight but I started losing my hair so I stop taking it but my desire to lose weight made me go back to doctor and I decided to take adipex which is a lot more expensive but the reaction I have to it is not the same I sit on bed and cry I'm very tired and can't fall asleep so makes me moody is just weird that the same the pills contain the same stuff I don't think so and also with adipex you do lose a lot more faster I say you lose a pound a day but the reaction is different I'm still taking adipex but thinking of stoping and going back to phentemine but the part of losing my hair is scary but I like that I not tired I have energy and I'm interested in sex ever since I started adipex I have no interest in sex I'm so so so tired have no interest for anything
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+2 # which is best?antoniojones1968 2012-08-27 22:20
I know there isn’t too much of a difference and they must be chemically the same, but sometimes I find that there is a difference between the generic and brand name of drugs. Has anyone tried both and seen a difference?
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-1 # a rose by any other namebrightstar 2012-02-02 04:22
There are so many different names for the same medications out there that it can be hard to keep up. It’s good to inform yourself so that you know when two popular names like these are the same thing. :lol:
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+2 # christy 2011-10-25 04:48
There really isn't enough information like this around since most sites say that they are the exact same drugs and that's it. I realize that they're the same medication, but it's important to know that their inactive ingredients are different in case you prefer one over the other or if you've had unpleasant experiences with one and not the other.
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0 # jan 2011-10-10 03:15
I was pretty surprised when I read this article. I'd always thought that the two pills were the exact same drug, only one had a brand name stamp on it so that it could come with a bigger price tag. Thanks for this helpful little tidbit. It's good to know.
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